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Association between obesity, high-sensitivity C-reactive protein 2 mg/L, and subclinical atherosclerosis: implications of JUPITER from the Multi-Ethnic Study of Atherosclerosis

Obesity significantly increases loading forces on the knees, hips, ankles, and spine, accelerating cartilage degradation and contributing to osteoarthritis development and progression

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These components exhibit potent antioxidant activity by scavenging reactive oxygen species (ROS), inhibiting lipid peroxidation, and protecting hepatocytes from apoptosis