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As you age, NAD levels naturally decline

Another metabolic pathway involves the enzyme, glutamine synthetase, present in several tissues, which converts ammonia with glutamate into glutamine, achieving its renal secretion through the synthesis of urea from glutamine

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However, when inflammation becomes chronic or damage outpaces repair, problems develop

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Supplements that support tirzepatide include a high-quality multivitamin (to compensate for reduced food intake), magnesium citrate (helps with constipation and sleep), omega-3 fatty acids (anti-inflammatory support), and vitamin D (often depleted in people with obesity)