any metabolic inefficiencysuch as insulin resistancediverts resources and increases oxidative stress in neural tissue
Another group severe insulin resistance makes up 18% of the diabetes population
These mechanisms have been demonstrated primarily in laboratory and animal studies
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In this large, propensity-matched, cohort study, individuals with overweight or obesity treated with tirzepatide were significantly more likely to achieve clinically meaningful weight loss and larger reductions in body weight compared with those treated with semaglutide, the researchers said.