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The peptide stimulates the activity of enzymes involved in ceramide biosynthesis, including serine palmitoyltransferase and ceramide synthase

Lactate further augments neutrophil functions, including chemotaxis, phagocytosis, oxidative burst and neutrophil extracellular trap formation, via energy provision and PI3K/Akt signaling, which may exacerbate tissue cell ferroptosis (105)

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In Phase 3 clinical trials, it helped adults without diabetes lose up to 22.7% of their body weight over 68 weeks, and adults with type 2 diabetes lose up to 15.7%

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