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However, the needle used is very fine, and the discomfort is minimal and short-lived

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Further clarity is required around the optimal timing of combination and sequential add-on therapy initiation

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The microvasculature of the kidney has similar functions to the microvascular systems of other organs, including the delivery of sufficient oxygen and nutrients to tissue cells, maintenance of the integrity of the endothelial monolayer, maintenance of the anticoagulant/procoagulant balance, and promotion of leukocyte recruitment (82)

Participants on tirzepatide lost 20.2% of body weight on average, compared to 13.7% on semaglutide