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Orforglipron, an Oral GLP-1 Receptor Agonist for Obesity Treatment, New England Journal of Medicine, 2025

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Cortical thickness in insular subregions has been reported to be negatively associated with nicotine dependence (27, 28), and nicotine dependence severity has been positively correlated with activation of the anterior and posterior insula in response to smoking-related cues (29)

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