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Amidated peptides have been observed to exhibit reduced sensitivity to proteolytic degradation and, in some cases, increased receptor binding affinity relative to their acid-form counterparts (2)

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Clin Cancer Res 12:1828-1838, 2006

In the near future, doctors and patients will probably have to trial-and-error their way to what works best

[1] [2] Women of childbearing potential should use effective contraception during treatment and discuss family planning with their healthcare provider well in advance

Additionally, peritoneal macrophages exhibit reduced phagocytic activity due to downregulated CD36 expression, allowing ectopic endometrial cells to evade clearance