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[2] Patients should contact their GP if they experience: Side effects from B12 injections (though these are rare and usually mild) Difficulty attending scheduled injection appointments, as missed doses may lead to symptom recurrence New symptoms developing during treatment Concerns about treatment effectiveness or duration Changes in other medications that might affect B12 absorption Suspected adverse reactions to B12 treatment can be reported through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

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The metabolic sensors in these cells respond to glucose as described above, and GLP-1 treatment reversed the glucose effects [83]

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Neurologic causes Neurologic weakness requires neurologic coding when documented: stroke-related deficits neuropathy patterns radiculopathy deficits progressive neurologic disease findings Muscle weakness coding does not replace neurologic diagnosis coding when a neurologic cause is established

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