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Laboratory and animal studies suggest GLP-1 receptor agonists may also inhibit nuclear factor-kappa B (NF-B) signaling, a key pathway in inflammatory gene expression, and reduce oxidative stress through enhanced antioxidant enzyme activity

[4] Five-year survival rates are 98% in the United States

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Statistical significance was assessed using analysis of variance (ANOVA) with Dunnetts post hoc test for comparisons involving more than three groups, and an unpaired two-tailed Students t test for comparisons between two groups

10.1523/JNEUROSCI.5069-13.2014 138 SunheY