As many studies have also reported, this provides a wide range of benefits for both diabetics and non-diabetics, including: Weight loss Lowered risk of strokes and heart attacks Reduced inflammation Reduced stress hormones Reduced risk of cancer Reduced risk of age-related diseases Reduced risk of diabetes Reduced risk of dementia Improved PCOS However, Metformins potential benefits are not just limited to its ability to lower blood sugar levels
Similarly, chronic therapy with metformin specifically increases plasma total GLP-1 levels in diabetic and non-diabetic participants [18]
GLP-1 medications work by mimicking the effects of this naturally occurring hormone, providing a range of potential therapeutic benefits
Researchers are already testing triple-agonist drugs, such as retatrutide, which target GLP-1, GIP and glucagon receptors
Diabetes: advances in diagnosis and treatment
Obesity (Silver Spring, Md.), 19 (9), 17961803