Ferroptosis in tumor cells triggers damage-associated molecular patterns (DAMPs), releasing cytokines to stimulate adaptive immunity, thereby promoting the immunogenic cell death (ICD) of tumor cells [87]
Pastore, P., Roverso, M., Tedesco, E., Micheletto, M., Mantovan, E., Zanella, M., et al
Grx1, a 12-kDa class I Grx with CPYC active site, is mainly found in the cytosol but can also enter the nucleus or be exported from the cell [23,24]
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This analysis strengthens the increasing body of work identifying altered antioxidant responses as a potential contributor to cognitive impairment
The first and best-characterized mechanism is the AMPK pathway