Retatrutide does not currently hold a UK marketing authorisation from the MHRA, so it cannot be prescribed through NHS or private channels
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Wegovy contains semaglutide, which mimics one natural hormone in your body, while Mounjaro contains tirzepatide, which mimics two hormones
For levothyroxine specifically, slower gastric emptying could theoretically reduce how much hormone reaches your bloodstream in a given timeframe, potentially lowering your effective dose
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How the Dose Titration Affects Symptoms Most people notice side effects more intensely when they first start the medication or when they move to a higher dose