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Lancet Reg Health-Europe

Phase 3 Update: TRIUMPH-4 Results Preliminary data from the ongoing Phase 3 TRIUMPH-4 trial (68 weeks) shows higher numbers than Phase 2: 12mg dose: 28.7% average weight loss (~71 lbs / 32 kg) 9mg dose: 26.4% average weight loss (~64 lbs / 29 kg) Knee osteoarthritis pain: 76% reduction (significant quality-of-life improvement) Blood pressure: Average reduction of 14 mmHg Full Phase 3 results across the TRIUMPH program (obesity, diabetes, cardiovascular outcomes, kidney outcomes) are expected throughout 2026

This contributes to national pharmacovigilance and helps the MHRA identify emerging safety signals from unregulated products

These agreements typically specify quarterly or monthly order quantities, fixed pricing for an agreed period (usually 6-12 months), quality specifications and testing requirements, payment terms, and dispute resolution procedures

On MyObesityTeam, more than 57,000 members come together to ask questions, give advice, and share their stories with others who understand life with obesity

Expected US launch price is being estimated by analysts to be between $900$1,500/month, with insurance coverage uncertain