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Pancreatic steatosis associates with impaired insulin secretion in genetically predisposed individuals
Dual modifications, such as 2,4- and 2,5-sugar modifications, have been employed in the development of siRNA therapeutics to further expand the potential of ribose modifications
GLORY-3, currently ongoing, directly compares mazdutide to semaglutide in people with obesity and metabolic-associated fatty liver disease
The sensitivity analysis (individuals with BMI 30 kg/m 2 ) generally reinforced findings from the BMI 27 kg/m 2 population, with both GLP-1 RAs demonstrating consistent associations with better ocular outcomes compared to traditional anti-obesity medications (Fig
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