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Heres the reality: in human studies, oral L-carnitine can raise muscle carnitine levels by up to about 2025% when dosed correctly and consistently, but only after weeks of use

2013 Mar;61(3):233-9.

However, a recent clinical trial found contradictory results that 10 MT-II administration before bedtime reduced insulin sensitivity by 12% in men [3]

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The CV effect of oral semaglutide for patients with T2D and ASCVD and/or chronic kidney disease (CKD) was investigated in the SOUL trial (NCT03914326)