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Despite relatively high prevalence of both conditions and their debilitating impact on life (for example, one-quarter of ME/CFS patients are bed- or house-bound) [6], the understanding of mechanisms leading to the development of fatigue is poor

Excess hydroxocobalamin can bind to other plasma proteins such as albumin, which helps explain the very high B12 levels seen after injections of that form

Understanding this mechanism explains both the benefits and the potential for adverse reactions

Vascular Health and Risk Management , 541-548

Eczema was induced using lipopolysaccharide or a mixture of Staphylococcal enterotoxin B and house dust mite extract

doi: 10.1038/s41419-020-03253-8 181 ZhengSMaMChenYLiM