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FIGURE 2 3.2 GHK-Cu inhibited the expression of inflammatory cytokines in DSS-induced colitis mice Figures 3AD show that Western blot analysis detected marked elevations in IL-1, IL-6, and TNF- levels in colonic tissue of DSS-induced colitis mice, indicating a robust inflammatory response

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There were substantial translational challenges due to the discordance between preclinical drug databases and real-world clinical trajectories (54, 55)