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Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle MicroRNAs

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For patients who can pursue both, combining them in a structured protocol produces results that neither achieves alone because structural repair runs better when cellular energy is restored

Document injection-site reactions (redness, itching, nodules) and rotate injection sites regularly

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The resulting decrease in p62 leads to reduced sequestration of Keap1, thereby increasing Nrf2 stability and activating transcription of anti-ferroptosis genes [110]