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The FDA prescribing information for both Mounjaro and Zepbound does not list osteoporosis, bone loss, or fractures as known risks of the medication

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Furthermore, at the lowest dose tested (0.1 g kg 1 ), P5 showed improved efficacy at all time points and significantly decreased value of area under the curve (AUC

The honest framing has three parts: This is mechanistic reasoning, not a demonstrated effect