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The researchers found that GLP-1 RA users had higher rates of type 2 diabetes (55.6 percent versus 29.5 percent), hypertension (69.1 percent versus 52.7 percent), and chronic obstructive pulmonary disease (17.3 percent versus 6.5 percent)

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However, these models are important because they mimic pathology of NTG, including RGC loss, optic nerve atrophy, and visual impairment with normal IOP 2,3

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The CNS-mediated appetite-regulation mechanism is increasingly central to the current understanding, and the open research question is what fraction of the observed clinical signal is peripheral vs central

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