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In this review, the relations based on the currently available literature were explored

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Arachidonate 12-lipoxygenase (ALOX12) inactivation diminishes p53-mediated ferroptosis induced by ROS stress ( N1 -acetyltransferase 1 (SAT1) is a transcription target of p53, SAT1 expression induces lipid peroxidation and sensitizes cells to undergo ferroptosis upon ROS-induced stress, while knockout of SAT1 expression or pharmacologically inhibited ALOX15 partially abrogates p53-mediated ferroptosis (Ou et al., 2016)