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While the small intestine is commonly affected, inflammation can extend to deeper layers, causing life-threatening complications

Additionally, Cucurbitacin B (CuB) stimulates GLP-1 secretion via the bitter taste receptor TAS2R10 and, similar to Metformin, induces hypoglycemic effects in diabetic mice [194]

It is crucial to note that the prescribing information for both drugs did not disclose any risks associated with similar gastrointestinal events or issue warnings regarding the potential development of gastroparesis

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Thymosin 4: a multi-functional regenerative peptide