Monica Cortinovis, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy
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Notably, nutraceuticals like RSV, PPR, and QUE have been shown to inhibit CYP3A4 activity, thereby reducing systemic drug elimination rates and increasing toxicity risks due to prolonged drug retention in circulation (9, 21, 32, 54)
The prognosis of AE-IPF is poor, with mortality ranging from 78% to 96%
Mendelian randomization and genome wide association studies (GWAS) confirm that TG are causal in the atherogenesis pathway [58]