In preclinical models, researchers observed that abaloparatide treatment was associated with increased bone mineral density, trabecular connectivity, and cortical thickness
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Furthermore, when combined with anti-PD1 or anti-CTLA4 antibodies, CB-839 promotes the infiltration of effector T cells into tumors and upregulates IFN-associated gene expression, thereby enhancing the antitumor activity of these checkpoint inhibitors [199]
Our monoallelic system also enabled subtle binding differences between alleles within HLA supertypes to be unambiguously defined (Supplementary Fig
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