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This includes adults with an initial BMI of 30 kg/m 2 and above, or 27 to 29.9 kg/m 2 with at least one weight-associated comorbidity (e.g hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease, prediabetes or T2DM)

In an attempt to block glycine biosynthesis, researchers are using antimetabolites (drugs that interfere with the effects of metabolites), methotrexate, and pemetrexed to inhibit SHMT [134, 141]

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Incorporating vegetables, lean proteins, whole grains, and healthy fats into your meals helps fuel your body effectively

doi: 10.1016/S2468-1253(24)00188-2

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