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Intranasal oxytocin enhances connectivity in the neural circuitry supporting social motivation and social perception in children with autism

For background on the GHRH pathway that CJC-1295 targets, Wikipedias growth hormone-releasing hormone overview provides foundational context

Subcutaneous injection was chosen as 5A-1MQ specifically has poor oral bioavailability in mice, a phenomenon that does not occur in rats 26

It mediates tissue-protective signaling distinct from the erythropoietic EPO pathway

It triggers a clean GH pulse with minimal effect on cortisol or prolactin

Juvederm Ultra Plus was used We numb the lips with a lidocaine cream with epinephrine for 15-20 minutes prior to treatment