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The neuroprotective data shows protection against oxidative stress and hypoxia, two of the primary killers of neurons following injury
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We found that, when fused to the Usp45 secretion signal, GFP and TAT-GFP proteins were secreted with a similar efficacy, indicating that the positively charged TAT residues do not increase cytoplasmic proteolytic degradation or inhibit secretion of a TAT-fused protein
A higher percentage of the active compound reaching systemic circulation, and often, a faster onset of action
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Toxicology 241, 157166 (2007)
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