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While all of the mechanisms by which GLP-1 agonists assist with weight loss are not yet fully understood, below are the well-established ways in which these injectable medications can contribute to weight loss: GLP-1s stimulate the secretion of insulin and slow the release of glucagon, thereby keeping blood sugar low
doi: 10.3390/jcm14176159
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GLP-1 is a 30-amino acid peptide hormone produced by differential post-translational processing of the proglucagon precursor protein by prohormone convertase 1/3 (PCSK1) in intestinal L-cells and in neurons of the nucleus tractus solitarii (NTS) in the brainstem
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