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For this type of effort fatigue is caused by a drop in muscle ATP and the accumulation of metabolic acids, so this may reflect the dual effects of creatine and betaalanine supplementation

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If they have prominent occipital neuralgia , then I will give additional dosing over the correlating occipital nerves (I do this very commonly is most patients I treat)

And we had a really nitty gritty, professional level conversation here

Those supplements are legally sold as dietary supplements under a category the FDA recognizes