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Therefore, combining L-citrulline with GSH may augment the production of nitric oxide for better overall performance

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153 Through culturing BALF cells of COPD patients with healthy individuals, it was found that MMP-9 release by macrophages in COPD patients was significantly increased while healthy control macrophages released more TIMPs

Another small study in 2010 conducted at Sapienza Universitys Department of Clinical Medicine in Rome found that combining L-carnitine with caloric restriction helped reduce insulin resistance and increase sensitivity