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56 Azoospermia in particular has been correlated with increased risk of declining general health and death

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Xia Y, Sancho-Martinez I, Nivet E, Rodriguez Esteban C, Campistol JM, Izpisua Belmonte JC (2014) The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cells

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In young men, FOXO4 was predominantly found in the cytoplasm of Leydig cells, whereas in elderly men, it was primarily localized in the nucleus