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We considered a study to exhibit considerable heterogeneity if, following the statistical analysis, the I 2 statistic is equal to or greater than 30%

JP patent 10,033,161 Pastore A, Federici G, Bertini E, Piemonte F (2003) Analysis of glutathione: implication in redox and detoxification

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Excessive mitochondrial calcium accumulation disrupts oxidative phosphorylation and ATP synthesis, impairing cardiomyocyte contraction and relaxation [90]

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Another option for knee joint pain relief is the use of an unloader knee brace that shifts weight away from the problematic area