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Most people get enough from diet, but older adults, vegans, and those with certain medical conditions may require supplementation

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2 Similarly, people who have undergone gastrointestinal procedures, including weight loss surgery, may be at increased risk of vitamin B12 deficiency

The complete chemical structure of the molecule was determined by Dorothy Hodgkin based on crystallographic data and published in 1955 [147] and 1956, [148] for which, and for other crystallographic analyses, she was awarded the Nobel Prize in Chemistry in 1964