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Preclinical studies using germ-free or antibiotic-treated animals have demonstrated impaired muscle mass, mitochondrial function, and endurance capacity, which are restored upon colonization with healthy microbiota or supplementation with specific probiotics such as Lactobacillus plantarum TWK10 and Bifidobacterium longum OLP- 01 [72,73,74,75]
Mechanistic studies have established that Dihexas procognitive and synaptogenic effects are mediated by the hepatocyte growth factor (HGF) / c-Met receptor system rather than by the classical AT 4 receptor, despite Dihexas structural origin as an angiotensin IV derivative
While these findings are promising, more robust research is needed to establish long-term safety and efficacy
Our commitment to clean nutrition means this formula is USDA Certified Organic, completely vegan, non-GMO, and naturally gluten-free