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Research Evidence Comparison# CagriSema Research# The REDEFINE Phase 3 program provides robust evidence: REDEFINE 1 (3,417 participants, 20.4% weight loss at 68 weeks) and REDEFINE 2 (1,200 T2D participants, 13.7% weight loss)

Significant weight loss isnt always a benefit for older adults, especially if it means the loss of bone and muscle mass, which are critical for good physical health

Of that, Lillys orforglipron is expected to take 60% ($13.6B) versus just 21% ($4B) for Novos pill

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