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The accumulation of damaged DNA in the cytoplasm, which serves as a damage-associated molecular pattern (DAMP) to be recognized by DNA sensors, including the cGAS-STING pathway, is observed in aging cells

Storage Please store the product under the recommended conditions in the Certificate of Analysis

10.1016/j.pneurobio.2010.08.001 162 WangN.ZengG.-Z.YinJ.-L.BianZ.-X

Factors That Affect Results Age and Senescent Cell Burden Senescent cells accumulate exponentially with age

245 A coordinated series of signaling pathways are activated to regulate energy metabolism and preserve energy balance for vital physiological functions