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The function of GPX4 is precisely regulated by nuclear factor E2-related factor 2 (NRF2), a key transcription factor that activates the expression of various antioxidant genes, including those encoding GSH synthetase and superoxide dismutase (SOD), facilitating the clearance of excess ROS (Xie et al., 2016

Following the CTF refinement and non-uniform (NU) refinement, one last round of heterogenous refinement was carried out using three identical initial models (output of NU refinement)

Its also advisable to regularly check the medication for expiration dates and dispose of any unused or expired pills properly, following local guidelines for medication disposal

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0-70 min) is dose-dependently uptake by T47D cells with V max of 27.34 pmol/mg protein/min [4]