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C57BL/6-Glp1rem2(hGLP1R) Smoc mice (hGLP-1R mice, NM-HU-200220) were obtained from Shanghai Model Organisms Center (Shanghai, China)

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There is a boxed warning regarding thyroid C-cell tumors based on rodent studies, with a contraindication in patients with personal or family history of MTC or MEN2

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