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Researcher Loren Pickart, PhD, who first isolated GHK from human plasma, described it as having a "profound effect on the reset of human genes toward a more youthful state." More recent genomic analyses confirm that GHK-Cu shifts gene expression patterns in aging tissue toward patterns characteristic of much younger tissue effectively acting as a biological reset at the cellular level

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Consistent with findings in younger mice, plasma TG, apoB48, and apoB100 were not different in older Dpp4 Gut+/+ versus Dpp4 Gut/ mice after olive oil and tyloxapol administration (Figure 10, GI)

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