In the foregoing synthesis method of cagriltide, the specific step of cyclization in step four includes: dissolving the linear peptide crude product in acetonitrile water according to the dose that 1g of the linear peptide crude product is dissolved in 100mL of 50% acetonitrile water solution, adding purified water to dilute the linear peptide crude product to 1g/L after the linear peptide is dissolved
8 , eabq1475 (2022)
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Locigno R, Pincemail J, Henno A, Treusch G, Castronovo V
[DOI] [PubMed] [Google Scholar] 172.Dbrowska K, Kamierczak Z, Majewska J, Miernikiewicz P, Piotrowicz A, Wietrzyk J, et al