GLP-1 (glucagon-like peptide-1) is a hormone released from specialized cells in the small intestine called L-cells in response to food
Inflammation: Inflammation is regulated by DPP-4 clearance of proteins that modulate immune responses

However, contact your healthcare provider immediately if you experience: Call Right Away: Severe, persistent vomiting that prevents you from keeping down any fluids Signs of dehydration: dark urine, dizziness when standing, extreme fatigue, confusion Severe abdominal pain that doesn't improve or is getting worse Signs of pancreatitis: intense upper abdominal pain radiating to back, fever, nausea Allergic reaction: rash, swelling, difficulty breathing Low blood sugar symptoms (if you have diabetes): shaking, sweating, confusion, blood sugar below 70 mg/dL Vision changes (especially if you have diabetes) Call During Office Hours: Nausea so severe you can't eat anything for more than 24 hours Constipation lasting more than 4-5 days despite interventions Persistent heartburn not relieved by over-the-counter medication Questions about adjusting other medications (especially diabetes meds) Concerns about whether your symptoms are normal Normal First-Week Symptoms (Don't Need to Call): Reduced appetite Mild to moderate nausea, especially days 2-4 Feeling full very quickly Mild fatigue Some constipation Mild headaches Food aversions or different taste preferences Frequently Asked Questions What should I eat during my first week on Ozempic or Wegovy

Red blood cells live for roughly 120 days, making this measurement an excellent marker of glucose exposure over time
Key findings from studies A meta-analysis of 8 studies involving 964 patients found that semaglutide was associated with an average total weight loss of 10.97% following bariatric surgery
Altogether, these costs add up to nearly $114 billion