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Reported as a deNADding enzymes, the Nudt12 contributes to the decapping of RNA following exposure to nutrient stress, such as glucose deprivation, while DXO is responsible for the environmental stress, such as heat shock

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For LC-MS analysis, the target metabolites of the serum samples were analyzed using the Agilent 1290 UHPLC tandem Agilent 6460 triple quadrupole mass spectrometer