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Dentro de la poblacin ITT, 253 pacientes tratados con placebo y 122 tratados con orlistat tuvieron una reduccin de peso mnima o nula (igual o menor a 1% del peso corporal basal) despus de 1 ao de tratamiento

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Kawai Y, Uneda K, Yamada T, Kinguchi S, Kobayashi K, Azushima K, et al

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A history of the roles of cytochrome P450 enzymes in the toxicity of drugs

Diversit della Popolazione: La popolazione dello studio STEP 1 era pi giovane, pi sana e includeva una percentuale maggiore di donne rispetto a SELECT