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1 H NMR (500 MHz, DMSO) 7.95 (t, J = 38.4 Hz, 5H), 7.41 (p, J = 5.1, 3.9 Hz, 18H), 7.23 (d, J = 7.4 Hz, 2H), 7.09 (d, J = 7.4 Hz, 12H), 6.96 (d, J = 19.0 Hz, 2H), 6.70 (q, J = 9.2, 8.1 Hz, 4H), 4.56 (d, J = 54.2 Hz, 2H), 4.18 (d, J = 69.9 Hz, 3H), 3.56 (tt, J = 18.3, 9.3 Hz, 7H), 3.03 2.77 (m, 10H), 1.66 1.20 (m, 54H)

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We excluded the possibility that the first reaction phase reflects the deglutathionylation of roGFP2 WT since this would necessitate an earlier drastic increase of the fluorescence due to the opening of the disulfide bond in roGFP2 WT (S 2 )

Despite this, vaccines that elicit neutralizing antibodies against the S protein reliably protect animals from SARS-CoV challenge without evidence of enhancement of infection or disease 71,72,73

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