Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)
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weekly for 1 month, then monthly for 4 months, in cerebral and cognitive function, which were related to reductions in homocysteine
W., & Visser, G