Published studies have demonstrated that hydroquinone is a mutagen and a clastogen
Intriguingly, the KRT32 gene, which encodes keratin, exhibited the most significant association with PRP ( P = 3.06 10 4 ), reinforcing the critical role of keratinocytes in PRP pathogenesis
For instance, the efficacy of targeted pharmacotherapy to reduce central gain or aberrant cortical oscillationsmechanisms implicated in tinnitus generation (Hayes et al., 2021)could be potentiated by concurrent CBT to address maladaptive attentional and emotional responses
DAmico, G
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This is particularly relevant when we consider GSH pathways, as well as their transcriptional regulator Nrf2, for proliferation, survival and function of T cells, B cells and macrophages (Muri and Kopf, 2021)