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Albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, orforglipron and semaglutide used in the clinic are monoGLP-1RAs, tirzepatide acts not only on GLP1R, but also on glucose-dependent receptors of insulinotropic peptide (GIP), and retatrutide is a triple agonist of GLP-1, GIP and glucagon receptors

Release of peptide YY by fat in the proximal but not distal gut depends on an atropine-sensitive cholinergic pathway

Listen closely to your body's new fullness signals and stop eating before you feel stuffed

When used for weight loss, semaglutide is available under the brand name Wegovy

Your primary care provider can help you navigate health challenges

But other potential side effects can be more serious