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Interestingly, adventitial fibroblasts (AFs) exhibit the remarkable ability to transdifferentiate into VSMCs in response to microenvironmental cytokines, subsequently migrating to the luminal side of the vessel (66)

485 These findings indicate that mitochondria iron overload, combined with ROS formation and subsequent ferroptosis, intensifies the cardiotoxic effects of DOX-induced cardiomyopathy and may be an important mechanism

At the same time, multiple charge and discharge cycle tests can also be performed to observe the attenuation of capacity

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This method operates at moderate temperatures, which helps preserve the structural integrity and bioactivity of heat-sensitive polyphenols ( However, supercritical fluid extraction also has limitations

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