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G., and Harrop, G

This tricks the body into thinking GLP-1 levels are high, causing it to respond by: slowing down how quickly the stomach empties signalling to the brain that you are full increasing the release of insulin and insulin sensitivity This helps to improve blood sugar control, which is useful for patients with type 2 diabetes

678 Hirsch, I

Of the 3 asymptomatic hypoglycaemic episodes reported, 2 occurred in 2 participants in the normal hepatic function group, and 1 in a participant in the moderate impairment group, indicating no increased risk of hypoglycaemia with hepatic impairment in this trial

HY and AZ performed the meta-analysis and produced forest plots and summary results under the supervision of J-YW and C-SY