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If neurological involvement is suspected, treatment should be started urgently and must not be delayed whilst awaiting blood test results

Caffeine-free, preservative-free, and low calorie (9.5kcal)

Guidance on Multi-Dose Vials and Preservatives

Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, enhances mitochondrial respiratory chain complex I and V activity, restores ATP production, and improves overall mitochondrial function in CUMS models [47]

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This premature polyploidy in Ercc1 -deficient liver is most likely caused by increased levels of p21 in response to accumulating DNA damage (Chipchase, ONeill, and Melton 2003)